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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (15)GO (15) Nucleotides (61)Nucl. (61) Proteins (41)Prot. (41) Interactants (146)Interact. (146) Wiki
XB-GENEPAGE-6054020
???displayGene.symbol???:
 lck

???displayGene.name???: 
LCK proto-oncogene, Src family tyrosine kinase

???displayGene.synonyms???
p56lck , xlck ( Nomenclature history )

???displayGene.geneFunction???
tyrosine kinase

AI Protein Function :
lck is a Src family non‑receptor tyrosine kinase that functions in T‑cell receptor signaling by phosphorylating ITAM motifs and activating downstream effectors such as ZAP‑70 and LAT; it also participa...[+]


InterPro :
Kinase-like dom sf, SH2 dom sf, Lck SH3, SH3-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
immunodeficiency 22

MIM:
IMMUNODEFICIENCY 22; IMD22

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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