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Summary Expression Expr. PhenotypesPheno. Gene Literature (8)Lit. (8) GO Terms (67)GO (67) Nucleotides (56)Nucl. (56) Proteins (30)Prot. (30) Interactants (191)Interact. (191) Wiki
XB-GENEPAGE-6049122
???displayGene.symbol???:
 ern1

???displayGene.name???: 
endoplasmic reticulum to nucleus signaling 1

???displayGene.synonyms???
ire1 , ire1a , ire1 alpha , ire1p , LOC108701211 , xIRE1 [+] ( Nomenclature history )

???displayGene.geneFunction???
Serine/threonine protein kinase and endoribonuclease ERN1/IRE1, sensor of the unfolded protein response pathway

AI Protein Function :
ern1 encodes an endoplasmic reticulum membrane‑bound sensor with serine‑threonine kinase and RNase activities that initiates the unfolded protein response; it phosphorylates downstream signaling compon...[+]


InterPro :
IRE1/2-like, KEN dom, KEN sf, Kinase-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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