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Summary Expression Expr. PhenotypesPheno. Gene Literature (32)Lit. (32) GO Terms (96)GO (96) Nucleotides (268)Nucl. (268) Proteins (52)Prot. (52) Interactants (367)Interact. (367) Wiki
XB-GENEPAGE-5918987
???displayGene.symbol???:
 sqstm1

???displayGene.name???: 
sequestosome 1

???displayGene.synonyms???
p62 ( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein, contains ZZ-type Zn-finger

AI Protein Function :
sqstm1 is a signaling adaptor and scaffold protein that functions as a selective autophagy receptor, binding polyubiquitin chains through its UBA domain and linking cargo to LC3‑positive autophagosomes...[+]


InterPro :
SQSTM UBA, UBA-like sf, PB1 dom, PB1 p62, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
frontotemporal dementia and/or amyotrophic lateral sclerosis 3 [+]

MIM:
PAGET DISEASE OF BONE 2, EARLY-ONSET; PDB2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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