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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (17)Lit. (17) GO Terms (77)GO (77) Nucleotides (98)Nucl. (98) Proteins (51)Prot. (51) Interactants (192)Interact. (192) Wiki
XB-GENEPAGE-5904697
???displayGene.symbol???:
 jak3

???displayGene.name???: 
Janus kinase 3 (a protein tyrosine kinase, leukocyte)

???displayGene.synonyms???
E70 ( Nomenclature history )

???displayGene.geneFunction???
protein tyrosine kinase

AI Protein Function :
jak3 encodes a non‑receptor tyrosine kinase that participates in cytokine‑receptor signaling, phosphorylating downstream STAT proteins and regulating lymphocyte development; the protein localizes to th...[+]


InterPro :
Kinase-like dom sf, SH2 dom sf, Jak1 PHL dom, Ser-Thr/Tyr kinase cat dom, [+]

???displayGene.geneInteractants???
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Diseases: 


MIM:
SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, B CELL-P

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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