Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (24)GO (24) Nucleotides (65)Nucl. (65) Proteins (40)Prot. (40) Interactants (2)Interact. (2) Wiki
XB-GENEPAGE-5858610
???displayGene.symbol???:
 nlrc4

???displayGene.name???: 
NLR family, CARD domain containing 4

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
apoptosis regulator

AI Protein Function :
nlrc4 is a cytosolic NOD‑like receptor that assembles inflammasome complexes, activates caspase‑1, and promotes maturation of interleukin‑1β and interleukin‑18 in response to bacterial flagellin and ty...[+]


InterPro :
NLRC4 HD, DEATH-like dom sf, NACHT NTPase, P-loop NTPase, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
familial cold autoinflammatory syndrome [+]

MIM:
AUTOINFLAMMATION WITH INFANTILE ENTEROCOLITIS; AIFEC [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info