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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (4)Lit. (4) GO Terms (207)GO (207) Nucleotides (184)Nucl. (184) Proteins (73)Prot. (73) Interactants (1840)Interact. (1840) Wiki
XB-GENEPAGE-5768571
???displayGene.symbol???:
 lrrk2

???displayGene.name???: 
leucine-rich repeat kinase 2

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( Nomenclature history )

???displayGene.geneFunction???
tyrosine kinase

AI Protein Function :
lrrk2 encodes a large multidomain protein kinase with Roc‑GTPase and serine/threonine kinase activity, functioning as a signaling molecule that regulates cytoskeletal dynamics, vesicle trafficking and ...[+]


InterPro :
Ankyrin rpt-contain sf, ARM-like, ARM-type fold, COR, [+]

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Diseases: 


Disease Ontology:
Parkinson's disease 8 [+]

MIM:
PARKINSON DISEASE 8, AUTOSOMAL DOMINANT; PARK8

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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