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Summary Expression Expr. PhenotypesPheno. Gene Literature (26)Lit. (26) GO Terms (42)GO (42) Nucleotides (127)Nucl. (127) Proteins (55)Prot. (55) Interactants (247)Interact. (247) Wiki
XB-GENEPAGE-5765420
???displayGene.symbol???:
 chek2

???displayGene.name???: 
checkpoint kinase 2

???displayGene.synonyms???
Cds1 , chk2 , hucds1 , lfs2 , pp1425 , rad53 [+] ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
Chek2 encodes a serine/threonine protein kinase involved in DNA damage checkpoint signaling, phosphorylates p53 and CDC25C, mediates cell cycle arrest and apoptosis. The protein localizes to the nucleu...[+]


InterPro :
SMAD FHA dom sf, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
prostate cancer [+]

MIM:
PROSTATE CANCER [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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