XB-GENEPAGE-5765248
???displayGene.symbol???:
rnf168
???displayGene.name???:
ring finger protein 168, E3 ubiquitin protein ligase
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(
Nomenclature history )
???displayGene.geneFunction???
ubiquitin-protein ligase
AI Protein Function
:
rnf168 encodes an E3 ubiquitin ligase that mediates ubiquitination of histone H2A/H2AX at sites of DNA double‑strand breaks, facilitating recruitment of downstream repair factors and promoting both hom...[+]
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Diseases:
Disease Ontology:
RIDDLE syndrome
MIM:
RIDDLE SYNDROME; RIDL
External Links:
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