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Summary Expression Expr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (107)GO (107) Nucleotides (87)Nucl. (87) Proteins (40)Prot. (40) Interactants (544)Interact. (544) Wiki
XB-GENEPAGE-493996
???displayGene.symbol???:
 vhl

???displayGene.name???: 
von Hippel-Lindau tumor suppressor

???displayGene.synonyms???
vhl1 ( Nomenclature history )

???displayGene.geneFunction???
E3 ubiquitin ligase

AI Protein Function :
vhl encodes a substrate recognition component of a Cullin‑RING E3 ubiquitin‑ligase complex that mediates ubiquitination and proteasomal degradation of hypoxia‑inducible factor‑1α, thereby negatively re...[+]


InterPro :
VHL beta dom sf, VHL sf, VHL tumour suppress b/a dom, VHL alpha dom, [+]

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Diseases: 


Disease Ontology:
nonpapillary renal cell carcinoma [+]

MIM:
PHEOCHROMOCYTOMA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tegg131f10      


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