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Summary Expression Expr. PhenotypesPheno. Gene Literature (231)Lit. (231) GO Terms (108)GO (108) Nucleotides (126)Nucl. (126) Proteins (56)Prot. (56) Interactants (874)Interact. (874) Wiki
XB-GENEPAGE-487965
???displayGene.symbol???:
 nkx2-5

???displayGene.name???: 
NK2 homeobox 5

???displayGene.synonyms???
AR2 , csx , nkx-2.5 , Nkx-2.5 , nkx2.5 , nkx2-5-a [+] ( Nomenclature history )

???displayGene.geneFunction???
homeodomain transcription factor with role in cardiac development

AI Protein Function :
nkx2-5 encodes a nuclear homeobox transcription factor of the NK2 class that binds DNA to regulate cardiac gene expression. It is required for heart tube formation and myocardial differentiation. The p...[+]


InterPro :
Homeobox dom, Homeobox metazoa, Homeobox CS, Homeobox-like sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial atrial fibrillation [+]

MIM:
CONOTRUNCAL HEART MALFORMATIONS; CTHM [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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