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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (11)Lit. (11) GO Terms (62)GO (62) Nucleotides (44)Nucl. (44) Proteins (26)Prot. (26) Interactants (144)Interact. (144) Wiki
XB-GENEPAGE-487754
???displayGene.symbol???:
 casp8

???displayGene.name???: 
caspase 8

???displayGene.synonyms???
caspase 8 , caspase-8 , xcaspase 8 , xCaspase-8 ( Nomenclature history )

???displayGene.geneFunction???
apoptotic cysteine protease

AI Protein Function :
The casp8 protein is an initiator cysteine protease that mediates death‑receptor signaling and activates downstream executioner caspases, leading to apoptosis; it acts as a signaling molecule in the ex...[+]


InterPro :
CASP8/FADD-like regulator, Caspase-like dom sf, Caspase cys AS, Caspase his AS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autoimmune lymphoproliferative syndrome type 2B [+]

MIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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