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Summary Expression Expr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (32)GO (32) Nucleotides (229)Nucl. (229) Proteins (55)Prot. (55) Interactants (96)Interact. (96) Wiki
XB-GENEPAGE-487572
???displayGene.symbol???:
 alas2

???displayGene.name???: 
5'-aminolevulinate synthase 2

???displayGene.synonyms???
ALA-E , MGC89126 ( Nomenclature history )

???displayGene.geneFunction???
transferase

AI Protein Function :
The protein encoded by alas2 is a mitochondrial enzyme that catalyzes the condensation of glycine and succinyl‑CoA to produce δ‑aminolevulinic acid, the first committed step of heme biosynthesis; it su...[+]


InterPro :
Aminotransferase I/II, PyrdxlP-dep Trfase, 5aminolev synth preseq, PyrdxlP-dep Trfase major, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
sideroblastic anemia 1 [+]

MIM:
ANEMIA, SIDEROBLASTIC, 1; SIDBA1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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