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Summary Expression Expr. PhenotypesPheno. Gene Literature (240)Lit. (240) GO Terms (245)GO (245) Nucleotides (370)Nucl. (370) Proteins (50)Prot. (50) Interactants (1870)Interact. (1870) Wiki
XB-GENEPAGE-484285
???displayGene.symbol???:
 tp53

???displayGene.name???: 
tumor protein p53

???displayGene.synonyms???
p53 , Trp248 , tumor suppressor p53 , Xp53 , Xrel3 [-] ( Nomenclature history )

???displayGene.geneFunction???
transcription factor regulating cell cycle, apoptosis and TGF-beta signaling

AI Protein Function :
tp53 is a sequence‑specific DNA‑binding transcription factor that functions as a tumor suppressor. It localizes to the nucleus and regulates transcription of genes governing cell‑cycle arrest, apoptosi...[+]


InterPro :
p53 DNA-bd, p53/RUNT-type TF DNA-bd sf, p53 tetramer sf, p53 tetrameristn, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
chronic lymphocytic leukemia [+]

MIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
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???displayGene.mosmith??? tneu034a23      


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