Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (10)Lit. (10) GO Terms (22)GO (22) Nucleotides (59)Nucl. (59) Proteins (41)Prot. (41) Interactants (114)Interact. (114) Wiki
XB-GENEPAGE-484223
???displayGene.symbol???:
 acvrl1

???displayGene.name???: 
activin A receptor like type 1

???displayGene.synonyms???
acvrlk1 , alk-1 , alk1 , hht2 , orw2 , skr3 [+] ( Nomenclature history )

???displayGene.geneFunction???
activin receptor, serine/threonine protein kinase

AI Protein Function :
Acvrl1 encodes a plasma‑membrane serine/threonine kinase receptor that functions in the TGF‑β/BMP signaling pathway, mediating ligand‑dependent phosphorylation of SMAD proteins and regulating angiogeni...[+]


InterPro :
Protein kinase ATP BS, Ser/Thr kinase AS, Kinase-like dom sf, GS dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
hereditary hemorrhagic telangiectasia

MIM:
TELANGIECTASIA, HEREDITARY HEMORRHAGIC, TYPE 2; HHT2

External Links:
1/6
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info