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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (48)GO (48) Nucleotides (56)Nucl. (56) Proteins (31)Prot. (31) Interactants (199)Interact. (199) Wiki
XB-GENEPAGE-483759
???displayGene.symbol???:
 crb1

???displayGene.name???: 
crumbs 1, cell polarity complex component

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Fibrillins and related proteins containing Ca2+-binding EGF-like domains

AI Protein Function :
crb1 encodes a transmembrane scaffolding protein that participates in establishing apical membrane identity and epithelial cell polarity; it localizes to the apical plasma membrane and tight junctions,...[+]


InterPro :
ConA-like dom sf, EGF-like Ca-bd dom, EGF-like CS, EGF-like dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Leber congenital amaurosis 8 [+]

MIM:
PIGMENTED PARAVENOUS CHORIORETINAL ATROPHY; PPCRA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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