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Summary Expression Expr. PhenotypesPheno. Gene Literature (29)Lit. (29) GO Terms (162)GO (162) Nucleotides (186)Nucl. (186) Proteins (57)Prot. (57) Interactants (492)Interact. (492) Wiki
XB-GENEPAGE-483711
???displayGene.symbol???:
 jak2

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Janus kinase 2 (a protein tyrosine kinase)

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( Nomenclature history )

???displayGene.geneFunction???
protein tyrosine kinase

AI Protein Function :
jak2 encodes a cytoplasmic and nuclear non‑receptor tyrosine kinase of the JAK family that functions as a signaling molecule in cytokine‑dependent JAK‑STAT pathways, mediating erythropoietin, thrombopo...[+]


InterPro :
JAK2 FERM C-lobe, SH2 dom sf, PTK Jak2 rpt1, Jak1 PHL dom, [+]

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Diseases: 


Disease Ontology:
familial erythrocytosis 1 [+]

MIM:
LEUKEMIA, ACUTE MYELOID; AML [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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