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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (16)GO (16) Nucleotides (64)Nucl. (64) Proteins (52)Prot. (52) Interactants (29)Interact. (29) Wiki
XB-GENEPAGE-482884
???displayGene.symbol???:
 pappa

???displayGene.name???: 
pappalysin 1

???displayGene.synonyms???
LOC108698294 , LOC108700041 ( Nomenclature history )

???displayGene.geneFunction???
metalloendopeptidase

AI Protein Function :
pappa encodes a secreted metalloproteinase that cleaves insulin‑like growth factor binding proteins (IGFBP‑4, IGFBP‑5) thereby increasing IGF bioavailability, and is expressed in branchial arches, limb...[+]


InterPro :
ConA-like dom sf, LamG-like, MetalloPept cat dom sf, Myxo disulph rpt, [+]

???displayGene.geneInteractants???
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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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