Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (40)GO (40) Nucleotides (134)Nucl. (134) Proteins (61)Prot. (61) Interactants (257)Interact. (257) Wiki
XB-GENEPAGE-482150
???displayGene.symbol???:
 map2k4

???displayGene.name???: 
mitogen-activated protein kinase kinase 4

???displayGene.synonyms???
map2k4-a , map2k4-b , xmek2 ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
map2k4 is a dual‑specificity protein kinase that acts as a signaling molecule in the JNK cascade, phosphorylating MAPK8 and MAPK9; it localizes to both cytoplasm and nucleus. It is required for converg...[+]


InterPro :
Kinase-like dom sf, Protein kinase ATP BS, Ser/Thr kinase AS, Prot kinase dom

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info