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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (185)GO (185) Nucleotides (219)Nucl. (219) Proteins (59)Prot. (59) Interactants (143)Interact. (143) Wiki
XB-GENEPAGE-481915
???displayGene.symbol???:
 psen1

???displayGene.name???: 
presenilin 1

???displayGene.synonyms???
X-PS-alpha , X-PS-beta ( Nomenclature history )

???displayGene.geneFunction???
intracellular signaling

AI Protein Function :
psen1 encodes a multi‑pass membrane protein that functions as the catalytic core of the γ‑secretase complex, mediating intramembrane cleavage of Notch receptors and amyloid precursor protein, thereby i...[+]


InterPro :
Preselin/SPP, Presenilin C, Peptidase A22A

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Alzheimer's disease 3 [+]

MIM:
ALZHEIMER DISEASE 3; AD3 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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