Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (15)Lit. (15) GO Terms (25)GO (25) Nucleotides (87)Nucl. (87) Proteins (46)Prot. (46) Interactants (123)Interact. (123) Wiki
XB-GENEPAGE-481464
???displayGene.symbol???:
 kremen1

???displayGene.name???: 
kringle containing transmembrane protein 1

???displayGene.synonyms???
kremen , kremen 1 , krm1 ( Nomenclature history )

???displayGene.geneFunction???
dickkopf receptor

AI Protein Function :
kremen1 encodes a single‑pass transmembrane receptor that binds dickkopf1 and modulates canonical wnt/β‑catenin signaling, acting as a negative regulator of pathway activity. It localizes to the plasma...[+]


InterPro :
Sperma CUB dom sf, CUB dom, WSC carb-bd, Kremen rcpt, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
ectodermal dysplasia 13

MIM:
ECTODERMAL DYSPLASIA 13, HAIR/TOOTH TYPE; ECTD13

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info