Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (30)Lit. (30) GO Terms (67)GO (67) Nucleotides (193)Nucl. (193) Proteins (53)Prot. (53) Interactants (431)Interact. (431) Wiki
XB-GENEPAGE-481306
???displayGene.symbol???:
 smad6

???displayGene.name???: 
SMAD family member 6

???displayGene.synonyms???
madh6 , Xsmad6 ( Nomenclature history )

???displayGene.geneFunction???
signal transduction, TGF-beta pathway

AI Protein Function :
The smad6 protein functions as an intracellular inhibitory SMAD that antagonizes BMP signaling, thereby modulating dorsoventral patterning and neural crest induction; it is expressed in the neural plat...[+]


InterPro :
MAD homology MH1, SMAD FHA dom sf, SMAD MH1 sf, SMAD dom Dwarfin-type, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
aortic valve stenosis [+]

MIM:
AORTIC VALVE DISEASE 2; AOVD2 [+]

External Links:
1/3
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tgas073h08      


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info