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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (5)Lit. (5) GO Terms (131)GO (131) Nucleotides (57)Nucl. (57) Proteins (35)Prot. (35) Interactants (98)Interact. (98) Wiki
XB-GENEPAGE-481144
???displayGene.symbol???:
 tlr2

???displayGene.name???: 
toll like receptor 2

???displayGene.synonyms???
LOC108699311 , LOC108706656 ( Nomenclature history )

???displayGene.geneFunction???
Toll/interleukin receptor and related proteins containing LRR and TIR repeats

AI Protein Function :
tlr2 is a membrane‑bound pattern recognition receptor that detects bacterial lipoproteins and lipopeptides. It signals through MyD88 to activate NF‑κB and induces expression of inflammatory cytokines s...[+]


InterPro :
Leu-rich rpt, Leu-rich rpt typical-subtyp, LRR dom sf, TIR dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
colorectal cancer

MIM:
LEPROSY, SUSCEPTIBILITY TO, 3; LPRS3 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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