Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (21)Lit. (21) GO Terms (182)GO (182) Nucleotides (186)Nucl. (186) Proteins (57)Prot. (57) Interactants (703)Interact. (703) Wiki
XB-GENEPAGE-480854
???displayGene.symbol???:
 apc

???displayGene.name???: 
APC regulator of Wnt signaling pathway

???displayGene.synonyms???
adenomatosis polyposis coli , xapc ( Nomenclature history )

???displayGene.geneFunction???
tumor suppressor

AI Protein Function :
apc encodes a large scaffold tumor suppressor protein that functions in the canonical wnt signaling pathway by forming the β‑catenin destruction complex, regulates microtubule dynamics and cell adhesio...[+]


InterPro :
Armadillo, APC N, Apc fam, APC 15aa rpt, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
familial adenomatous polyposis [+]

MIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
1/4
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info