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Summary Expression Expr. PhenotypesPheno. Gene Literature (54)Lit. (54) GO Terms (275)GO (275) Nucleotides (417)Nucl. (417) Proteins (90)Prot. (90) Interactants (585)Interact. (585) Wiki
XB-GENEPAGE-479153
???displayGene.symbol???:
 app

???displayGene.name???: 
amyloid beta precursor protein

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beta-amyloid precursor protein , MGC88882 ( Nomenclature history )

???displayGene.geneFunction???
amyloidogenic glycoprotein

AI Protein Function :
app is a type I transmembrane glycoprotein that serves as a precursor of amyloid‑β peptide and functions as a cell‑adhesion molecule and signaling modulator. It localizes to the plasma membrane, endocy...[+]


InterPro :
Amyloid Cu-bd sf, Prtase inh Kunz-CS, Amyloid glyco Cu-bd, Amyloid glyco Abeta, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Alzheimer's disease [+]

MIM:
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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