Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (4)Lit. (4) GO Terms (29)GO (29) Nucleotides (559)Nucl. (559) Proteins (73)Prot. (73) Interactants (179)Interact. (179) Wiki
XB-GENEPAGE-478727
???displayGene.symbol???:
 impdh2

???displayGene.name???: 
IMP (inosine 5'-monophosphate) dehydrogenase 2

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
rate-limiting enzyme in de novo guanine nucleotide biosynthesis

AI Protein Function :
impdh2 encodes a cytosolic inosine‑monophosphate dehydrogenase that catalyzes the NAD⁺‑dependent oxidation of inosine‑5′‑monophosphate to xanthosine‑5′‑monophosphate, the rate‑limiting step of guanine ...[+]


InterPro :
Aldolase TIM, CBS dom, IMP DH, IMP DH GMPRt, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


MIM:
IMPDH2 ENZYME ACTIVITY, VARIATION IN; IMPDH2V

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info