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Summary Expression Expr. PhenotypesPheno. Gene Literature (19)Lit. (19) GO Terms (144)GO (144) Nucleotides (221)Nucl. (221) Proteins (57)Prot. (57) Interactants (361)Interact. (361) Wiki
XB-GENEPAGE-478586
???displayGene.symbol???:
 tgfbr1

???displayGene.name???: 
transforming growth factor beta receptor I

???displayGene.synonyms???
aat5 , acvrlk4 , alk-5 , alk5 , lds1a , lds2a [+] ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
tgfbr1 is a transmembrane serine/threonine kinase receptor that mediates TGF‑β signaling by phosphorylating SMAD2/3, thereby regulating cell proliferation, differentiation and morphogenetic movements; ...[+]


InterPro :
Kinase-like dom sf, TGFB receptor, Protein kinase ATP BS, GS dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Loeys-Dietz syndrome [+]

MIM:
AUDITORY NEUROPATHY, AUTOSOMAL DOMINANT 1; AUNA1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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