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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (3)GO (3) Nucleotides (6)Nucl. (6) Proteins (7)Prot. (7) Interactants (48)Interact. (48) Wiki
XB-GENEPAGE-29086742
???displayGene.symbol???:
 duoxa2

???displayGene.name???: 
dual oxidase maturation factor 2

???displayGene.synonyms???
LOC101733132 , LOC108710293 ( Nomenclature history )

???displayGene.geneFunction???
This gene encodes an endoplasmic reticulum protein that is necessary for proper cellular localization and maturation of functional dual oxidase 2. In humans, mutations in this gene have been associated with thyroid dyshormonogenesis 5

AI Protein Function :
duoxa2 is a membrane‑bound endoplasmic reticulum protein that functions as a maturation factor for dual oxidase enzymes, facilitating their proper folding, stability and trafficking to the plasma membr...[+]


InterPro :
Dual oxidase maturation fac

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
thyroid dyshormonogenesis 5

MIM:
THYROID DYSHORMONOGENESIS 5; TDH5

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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