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Summary Expression Expr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (11)GO (11) Nucleotides (8)Nucl. (8) Proteins (9)Prot. (9) Interactants (0)Interact. (0) Wiki
XB-GENEPAGE-29084198
???displayGene.symbol???:
 irs2

???displayGene.name???: 
insulin receptor substrate 2

???displayGene.synonyms???
irsu , LOC100498409 , LOC108708462 , LOC108709741 ( Nomenclature history )

AI Protein Function :
irs2 is an intracellular signaling adaptor protein that links insulin and insulin‑like growth factor receptors to downstream pathways. It functions in the activation of PI3K‑Akt signaling and MAPK casc...[+]


InterPro :
IRS, IRS PTB, PH-like dom sf, PH domain

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
type 2 diabetes mellitus

MIM:
TYPE 2 DIABETES MELLITUS; T2D

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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