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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (12)GO (12) Nucleotides (15)Nucl. (15) Proteins (14)Prot. (14) Interactants (1)Interact. (1) Wiki
XB-GENEPAGE-29080114
???displayGene.symbol???:
 tomt

???displayGene.name???: 
transmembrane O-methyltransferase homolog

???displayGene.synonyms???
comt2 , LOC100490284 , LOC108706086 , LOC108710088 ( Nomenclature history )

???displayGene.geneFunction???
This gene encodes a catechol-O-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to a hydroxyl group of catechols and is essential for auditory and vestibular function.

AI Protein Function :
tomt is a transmembrane O‑methyltransferase localized to the Golgi apparatus and required for mechanosensory hair cell function in the inner ear and lateral line neuromasts. It mediates methylation rea...[+]


InterPro :
SAM-dependent MTases sf, SAM O-MeTrfase

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
nonsyndromic deafness

MIM:
DEAFNESS, UNILATERAL

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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