Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (38)GO (38) Nucleotides (64)Nucl. (64) Proteins (46)Prot. (46) Interactants (20)Interact. (20) Wiki
XB-GENEPAGE-492350
???displayGene.symbol???:
 syne2

???displayGene.name???: 
spectrin repeat containing, nuclear envelope 2

???displayGene.synonyms???
edmd5 , LOC108698815 , nesprin-2 , nua , nuance , syne-2 [+] ( Nomenclature history )

???displayGene.geneFunction???
Dystonin, GAS (Growth-arrest-specific protein), and related proteins

AI Protein Function :
syne2 encodes a spectrin‑repeat nuclear envelope protein that anchors the cytoskeleton to the nucleoskeleton as part of the LINC complex; it localizes to the outer nuclear membrane and perinuclear cyto...[+]


InterPro :
Actinin actin-bd CS, Anc-1/SYNE1/2-like, CH dom, CH dom sf, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Emery-Dreifuss muscular dystrophy [+]

MIM:
EMERY-DREIFUSS MUSCULAR DYSTROPHY 5, AUTOSOMAL DOMINANT; EDMD5

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info