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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (57)GO (57) Nucleotides (185)Nucl. (185) Proteins (61)Prot. (61) Interactants (106)Interact. (106) Wiki
XB-GENEPAGE-947838
???displayGene.symbol???:
 spast

???displayGene.name???: 
spastin

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
AAA+-type ATPase

AI Protein Function :
spast encodes an AAA ATPase microtubule‑severing enzyme that regulates microtubule dynamics during neuronal development and axon outgrowth. It functions in the brain, spinal cord, neural tube and eye, ...[+]


InterPro :
P-loop NTPase, ATPase AAA core, Vps4 C, MIT dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
hereditary spastic paraplegia 4

MIM:
SPASTIC PARAPLEGIA 4, AUTOSOMAL DOMINANT; SPG4

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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