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Summary Expression Expr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (60)GO (60) Nucleotides (196)Nucl. (196) Proteins (91)Prot. (91) Interactants (211)Interact. (211) Wiki
XB-GENEPAGE-1014005
???displayGene.symbol???:
 kalrn

???displayGene.name???: 
kalirin RhoGEF kinase

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( Nomenclature history )

???displayGene.geneFunction???
Guanine nucleotide exchange factor for Rho and Rac GTPases

AI Protein Function :
kalrn encodes a large multidomain Rho guanine nucleotide exchange factor that activates RAC1 and RHOA, regulating actin cytoskeleton dynamics; it functions in neuronal differentiation, dendritic spine ...[+]


InterPro :
DH-domain, PH domain, DBL dom sf, SH3 domain, [+]

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Diseases: 


MIM:
CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 5

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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