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Summary Expression Expr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (11)GO (11) Nucleotides (284)Nucl. (284) Proteins (76)Prot. (76) Interactants (50)Interact. (50) Wiki
XB-GENEPAGE-1013558
???displayGene.symbol???:
 elmo2

???displayGene.name???: 
engulfment and cell motility 2

???displayGene.synonyms???
elmo-2 ( Nomenclature history )

???displayGene.geneFunction???
Regulator of Rac1, required for phagocytosis and cell migration

AI Protein Function :
elmo2 is a Rac guanine nucleotide‑exchange factor that acts as a signaling molecule mediating actin cytoskeleton remodeling, cell migration and phagocytic engulfment; it activates Rac1 during gastrulat...[+]


InterPro :
ARM-like, PH domain, ELMO dom, PH-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


MIM:
VASCULAR MALFORMATION, PRIMARY INTRAOSSEOUS; VMPI

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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