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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (24)GO (24) Nucleotides (52)Nucl. (52) Proteins (31)Prot. (31) Interactants (0)Interact. (0) Wiki
XB-GENEPAGE-1012825
???displayGene.symbol???:
 hsd11b2

???displayGene.name???: 
hydroxysteroid (11-beta) dehydrogenase 2

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Corticosteroid 11-beta-dehydrogenase and related short chain-type dehydrogenases

AI Protein Function :
hsd11b2 encodes an NAD‑dependent 11β‑hydroxysteroid dehydrogenase type 2 enzyme that catalyzes the oxidation of cortisol to cortisone, thereby limiting activation of mineralocorticoid receptors; the pr...[+]


InterPro :
NAD(P)-bd dom sf, Sc DH/Rdtase CS, SDR fam

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
obsolete apparent mineralocorticoid excess [+]

MIM:
APPARENT MINERALOCORTICOID EXCESS; AME

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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