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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (26)GO (26) Nucleotides (205)Nucl. (205) Proteins (77)Prot. (77) Interactants (296)Interact. (296) Wiki
XB-GENEPAGE-1012658
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 herc2

???displayGene.name???: 
HECT and RLD domain containing E3 ubiquitin protein ligase 2

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( Nomenclature history )

???displayGene.geneFunction???
RCC1 domain

AI Protein Function :
herc2 encodes a HECT‑type E3 ubiquitin‑protein ligase localized to the nucleus that participates in DNA damage response, ubiquitination of DNA‑repair factors and regulation of chromatin stability; expr...[+]


InterPro :
Beta-propeller rpt TECPR, APC su10/DOC dom, Cyt B5-like heme/steroid sf, RCC1/BLIP-II, [+]

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Diseases: 


Disease Ontology:
Prader-Willi syndrome [+]

MIM:
SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 1; SHEP1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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