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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (108)GO (108) Nucleotides (121)Nucl. (121) Proteins (56)Prot. (56) Interactants (151)Interact. (151) Wiki
XB-GENEPAGE-1012364
???displayGene.symbol???:
 ripk1

???displayGene.name???: 
receptor interacting serine/threonine kinase 1

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs

AI Protein Function :
ripk1 encodes a serine/threonine protein kinase that acts as a signaling molecule in tumor necrosis factor pathways, mediating NF‑κB activation, apoptosis and necroptosis; it regulates inflammatory sig...[+]


InterPro :
DEATH-like dom sf, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
immunodeficiency 57

MIM:
IMMUNODEFICIENCY 57 WITH AUTOINFLAMMATION; IMD57

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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