Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (25)GO (25) Nucleotides (60)Nucl. (60) Proteins (38)Prot. (38) Interactants (64)Interact. (64) Wiki
XB-GENEPAGE-1011572
???displayGene.symbol???:
 tmprss6

???displayGene.name???: 
transmembrane serine protease 6

???displayGene.synonyms???
irida ( Nomenclature history )

???displayGene.geneFunction???
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface.

AI Protein Function :
tmprss6 encodes a type II transmembrane serine protease localized to the plasma membrane with an extracellular catalytic domain; the protein participates in iron homeostasis by modulating hepcidin acti...[+]


InterPro :
CUB dom, LDL receptor-like sf, LDrepeatLR classA rpt, Peptidase S1 PA, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
microcytic anemia

MIM:
IRON-REFRACTORY IRON DEFICIENCY ANEMIA; IRIDA

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info