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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (37)GO (37) Nucleotides (139)Nucl. (139) Proteins (44)Prot. (44) Interactants (25)Interact. (25) Wiki
XB-GENEPAGE-1009724
???displayGene.symbol???:
 ophn1

???displayGene.name???: 
oligophrenin 1

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Rho GTPase activator

AI Protein Function :
ophn1 encodes a Rho GTPase‑activating protein that modulates actin cytoskeleton dynamics and RhoA signaling. It functions as a signaling molecule that influences neuronal differentiation, axon guidance...[+]


InterPro :
AH/BAR dom sf, Rho GTPase activation prot, RhoGAP dom, PH domain, [+]

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Diseases: 


Disease Ontology:
syndromic intellectual disability

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, BILLUART TYPE; MRXSBL

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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