Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (19)GO (19) Nucleotides (93)Nucl. (93) Proteins (52)Prot. (52) Interactants (57)Interact. (57) Wiki
XB-GENEPAGE-1009303
???displayGene.symbol???:
 hlcs

???displayGene.name???: 
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Biotin holocarboxylase synthetase/biotin-protein ligase

AI Protein Function :
hlcs encodes a biotin‑protein ligase that catalyzes the covalent attachment of biotin to carboxylase enzymes, enabling biotin‑dependent carboxylation reactions; the protein is classified as an enzyme l...[+]


InterPro :
aa-tRNA-synth II/BPL/LPL, Biotin-prot ligase N, Biotin CoA COase ligase, BPL LPL catalytic

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
holocarboxylase synthetase deficiency

MIM:
HOLOCARBOXYLASE SYNTHETASE DEFICIENCY

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info