Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (30)GO (30) Nucleotides (207)Nucl. (207) Proteins (42)Prot. (42) Interactants (101)Interact. (101) Wiki
XB-GENEPAGE-1006786
???displayGene.symbol???:
 trim8

???displayGene.name???: 
tripartite motif containing 8

???displayGene.synonyms???
LOC108697420 ( Nomenclature history )

???displayGene.geneFunction???
ubiquitin-protein ligase

AI Protein Function :
trim8 is an intracellular E3 ubiquitin‑protein ligase that localizes to the nucleus and cytoplasm, mediates ubiquitination of target proteins, modulates NF‑κB signaling, and influences cell proliferati...[+]


InterPro :
Znf RING, Znf RING/FYVE/PHD, Znf RING CS, E3 ubiq-ligase TRIM/RNF, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
early infantile epileptic encephalopathy

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info