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Summary Expression Expr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (27)GO (27) Nucleotides (171)Nucl. (171) Proteins (46)Prot. (46) Interactants (82)Interact. (82) Wiki
XB-GENEPAGE-1004360
???displayGene.symbol???:
 espl1

???displayGene.name???: 
extra spindle pole bodies like 1, separase

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( Nomenclature history )

???displayGene.geneFunction???
Regulator of spindle pole body duplication

AI Protein Function :
espl1 encodes a separase protease that cleaves the cohesin subunit RAD21 to trigger sister chromatid separation during mitosis and is required for proper cytokinesis; the protein localizes to the nucle...[+]


InterPro :
Peptidase C50, SEPARIN core dom, TPR-like helical dom sf

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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