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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (23)GO (23) Nucleotides (119)Nucl. (119) Proteins (47)Prot. (47) Interactants (115)Interact. (115) Wiki
XB-GENEPAGE-1003599
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 top3a

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DNA topoisomerase III alpha

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xtop3a ( Nomenclature history )

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DNA topological change

AI Protein Function :
top3a encodes a DNA topoisomerase III alpha, a type IA topoisomerase that relaxes negatively super‑coiled DNA during replication, recombination and repair. It localizes to the nucleus and functions as ...[+]


InterPro :
Topo IA cen sub1, Topo IA cen sub2, Topo IA, Topo IA 2, [+]

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Diseases: 


Disease Ontology:
autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5

MIM:
MICROCEPHALY, GROWTH RESTRICTION, AND INCREASED SISTER CHROMATID EXCHANGE 2; MGR [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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